#hemoglobin #children #blood biochemistry+2

Blood Transfusion for Premature Babies: A New Perspective

28 octombrie 2025

2 min de lectură

Deschide ghid Deschide colecția Deschide seria

The largest randomized clinical trial on blood transfusion to premature babies was completed by Dr. Haresh Kirpalani of the University of Pennsylvania, Dr. Edward Bell of the University of Iowa, and colleagues from the Neonatal Research Network, including Dr. Rosemary Higgins of the George Mason University College of Health and Human Services. The study was published in the New England Journal of Medicine. To date, this is the most ambitious research in the world that examines blood transfusion in premature babies.

Concluzii cheie

The largest randomized clinical trial on blood transfusion to premature babies was completed by Dr.
When do babies need blood transfusions?
Evidence base

Pentru cine este

Persoane care explorează Pediatrics prin intermediul hemoglobin, children.

De ce contează

Acest articol te ajută să te orientezi rapid, apoi să treci la o colecție sau serie dacă vrei să continui.

Autorul articolului

Darya

Writer, Ornament

When do babies need blood transfusions?

Severely premature babies (born before 29 weeks of gestation) and those weighing 1–2 pounds or less are at high risk of developing anemia due to a reduced ability to produce red blood cells. This can even be fatal. Previous studies have shown that anemic children who received transfusions with a higher hemoglobin threshold were more likely to survive. According to statistics, premature babies are more likely to suffer from neurological disorders, but this was not associated with transfusion of blood oversaturated with erythrocytes.

Evidence base

Of the 845 infants who received high hemoglobin blood transfusions, 50.1 % died or survived with neurodevelopmental disabilities compared with 49.8 % of the 847 infants who received regular blood. The authors assessed the physical and mental development of children at the age of two and came to the conclusion that the number of red blood cells in the transfused blood does not affect mortality rate, and that transfusion of standard blood is safer for neurological development.

“The findings are likely to be used to guide the practice of blood transfusions in infants. Using RBC oversaturated blood was costly and difficult, and while we proved that it not only makes little sense, it can also be harmful," said Dr. Higgins. He went on to say that, “We will continue our research in the hope that we will find a way to increase the survival rate of children born with a weight of 1–2 pounds and below.”

New England Journal of Medicine, www.nejm.org/doi/10.1056/NEJMoa2020248 https://www.clinicaltrials.gov/ct2/show/NCT01702805

Continuă lectura

Pediatrics#children

How to Train the Vestibular Apparatus in Children

How do you know if your child has a weak vestibular apparatus? It could be that they get sick when traveling, easily lose coordination and balance, especially on uneven surfaces, or have a fear of falling. Or they could be afraid of taking the elevator and cycling. If this sounds familiar, how can you help your child?

Dr. Tatjana28 oct. 2025

Pediatrics#circumcision

Should Boys Be Circumcised?

Many parents ask this question based on health concerns. For example, hospitals in the United States do more than one million such procedures a year. However, the procedure is not as popular in Europe and Russia. Let’s take a look at this procedure from a medical point of view.

Dr. Alex28 oct. 2025

Cardiovascular health#heart attack

Even Slightly Elevated Thyroid Hormone Levels Can Cause Sudden Cardiac Arrest

The risk of death from a heart attack was found to be almost equal in patients with severely elevated thyroxine levels and those whose levels were normal but closer to the upper limit.

Darya28 oct. 2025

Skin, nails, hair#children

How To Manage Acne in Teenagers

It is hard enough to be a teenager. Teenagers experience mood swings, stress, and increased appetite — and acne on top of everything else. How can you help your child with acne?

Dr. Ihor28 oct. 2025

Instalează Ornament pentru a nu doar citi aceste articole, ci și pentru a-ți urmări sănătatea, a stoca rezultatele analizelor și a accesa alte funcții utile

Instalează Ornament