8 Reasons Why Some Women Can't Get Pregnant

28 ottobre 2025

2 min di lettura

Generally, if a couple has been attempting to conceive a child for one year and has not done so, they begin to explore the reasons. The causes of infertility may be hidden in the health of both women and men. Let’s look at the most common obstacles to motherhood for women.

Punti chiave

Generally, if a couple has been attempting to conceive a child for one year and has not done so, they begin to explore the reasons.
Rare or absent ovulation
Fallopian tube obstruction

Per chi è

Chi esplora Women's health attraverso pregnancy, women health.

Perché è importante

Questo articolo ti aiuta a orientarti rapidamente, per poi passare a una raccolta o serie se vuoi continuare.

Autore dell'articolo

Dr. Natalie

Obstetrician-gynecologist, ultrasound doctor

Rare or absent ovulation

This is one of the most common causes of female infertility, which can be caused by: – Polycystic ovarian syndrome(PCOS) – Hypothalamic dysfunction – Primary ovarian insufficiency – Prolactin levels that are too high

Fallopian tube obstruction

Damaged or blocked fallopian tubes prevent sperm from reaching the egg or block the passage of a fertilized egg into the uterus. The culprits are: – Pelvic inflammatory diseases – Infection of the uterus and fallopian tubes caused by sexually transmitted diseases – Previously undergone abdominal or pelvic surgery, including that associated with ectopic pregnancy

Endometriosis

Endometriosis is diagnosed when tissue that normally grows in the uterus overgrows outside of it. This pathology and its surgical removal can lead to scarring that can block the fallopian tubes and prevent the egg and sperm from connecting. Endometriosis can also make it difficult for a fertilized egg to implant.

Problems with the uterus or cervix

Both can interfere with the implantation of an egg, as well as increase the risk of miscarriage. These include: – Benign neoplasms: polyps, cysts, or tumors (myomas) – Congenital abnormalities (such as an unusual uterine shape) – Cervical stenosis (narrowing of the cervix)

Hormonal disruption

Any disruption of the endocrine system can lead to infertility.

Excessive immune response

In this case, the woman's body perceives sperm as pathogens and produces antibodies (immunoglobulins) against them.

Being underweight or overweight

With a small amount of fat layer, there is a failure in the rhythm of ovulation because at a low BMI, the level of estrogen decreases, and periods are lost. Excess body weight also negatively affects pregnancy. Even if conception occurs, there is an increased risk of fetal failure, as fatty tissue is a source of inflammation.

Long-term use of combined oral contraceptives

After withdrawal of OCs, a woman may not have menstruation and ovulation, as in 1-2 % of cases a syndrome of hyper inhibition of gonadotropic function of the pituitary gland develops.

The question of when to seek help from a doctor depends on the age of the woman. Up to 35 years of age, it is worth trying to conceive for one year before taking tests or undergoing treatment. Between the ages of 35 and 40, discuss your concerns with your doctor after six months of trying. After the age of 40, it is better to get tested beforehand.

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